Tetrodotoxin-Associated High Molecular Weight Substances from Toxic Pufferfish Liver.
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منابع مشابه
Larval pufferfish protected by maternal tetrodotoxin.
Marine pufferfish contain tetrodotoxin (TTX), an extremely potent neurotoxin. All species of the genus Takifugu accumulate TTX in the liver and ovaries, although the tissue(s) in which it is localized can differ among species. TTX is the major defense strategy the pufferfish appears to use against predators. TTX is also used as a male-attracting pheromone during spawning. Here we demonstrate an...
متن کاملTransfer profile of intramuscularly administered tetrodotoxin to non-toxic cultured specimens of the pufferfish Takifugu rubripes.
Tetrodotoxin (TTX) was intramuscularly administered to non-toxic cultured specimens of the pufferfish Takifugu rubripes to investigate TTX transfer/accumulation profiles in the pufferfish body. In two groups of test fish administered either 50MU/individual of TTX standard (purified TTX; PTTX) or crude extract of toxic pufferfish ovary (crude TTX; CTTX), TTX rapidly transferred from the muscle v...
متن کاملDifference in Uptake of Tetrodotoxin and Saxitoxins into Liver Tissue Slices among Pufferfish, Boxfish and Porcupinefish
Although pufferfish of the family Tetraodontidae contain high levels of tetrodotoxin (TTX) mainly in the liver, some species of pufferfish, boxfish of the family Ostraciidae, and porcupinefish of the family Diodontidae do not. To clarify the mechanisms, uptake of TTX and saxitoxins (STXs) into liver tissue slices of pufferfish, boxfish and porcupinefish was examined. Liver tissue slices of the ...
متن کاملHigh-molecular-weight folates of rat liver.
PATRICIA A. BARFORD, JOHN A. BLAIR and FREDERICK J. STAFF Department of Chemistry, University of Aston in Birmingham, Gosta Greem, Birmingham B4 7ET, U.K. It has been frequently claimed that polyglutamate forms of folates are found in animals (Noronha & Silverman, 1962; Shin et al., 1972; Brown et al., 1974) on the basis of column chromatography of these folates and chromatography of 'authentic...
متن کاملToxic substances from coal energy: an overview.
Environmental concerns over increased coal consumption are fully justified by the past history of coal use. Although improved technology has provided some safeguards, increased utilization will require mining practices, emission control technologies, and waste disposal procedures that are not yet fully integrated into the routine use of the coal energy system. The Committee on Health and Evniro...
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ژورنال
عنوان ژورنال: NIPPON SUISAN GAKKAISHI
سال: 1993
ISSN: 1349-998X,0021-5392
DOI: 10.2331/suisan.59.1177